NOT KNOWN FACTUAL STATEMENTS ABOUT NR1-SITE

Making use of this solution, Kalbaugh et al. assigned affinity and efficacy roles to positions within the LBDs from the NR1 and NR2A NMDAR subunits. In situ mutation of residues in immediate contact with certain ligand afflicted both efficacy and affinity, even though positions that stabilize the shut cleft conformation without a direct ligand inte